To increase COVID-19 vaccine confidence, project leaders created an online course titled Building COVID-19 Vaccine Confidence Among Nurses and Nursing Students, and in the Community. The course includes learning modules created to empower and boost confidence among students and nurses. Content focuses on communication strategies to equip nursing students with sound knowledge and concise and factual verbiage to promote the vaccine. The modules also include case studies and simulation activities to help students prepare for engaging with the school’s diverse campus and community. To provide opportunities for students to engage in conversations regarding vaccine hesitancy, the nursing school used their mobile recreational vehicle unit at town hall events on campus to share credible COVID-19 vaccine information and resource materials and foster conversations to address vaccine misinformation. In addition, the school partnered with the Southern Regional Area Health Education Center to provide continuing education using an online self-paced course for nurses titled Empowering Nursing Students and Nurses to Build Healthier Communities.